Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22958943 | 0.86 | LMNA (0.43) | MAPK1EGLN3LMNASMN1; SMN2TBXAS1 | |
| SCHEMBL9022352 | 0.82 | TBXAS1 (0.53) | LMNATBXAS1ALDH1A1 | |
| SCHEMBL908783 | 0.74 | — | — | |
| SCHEMBL15330515 | 0.73 | EGLN3 (0.46) | MAPK1EGLN3ESR1KMOLMNA | |
| Hydrochloric Acid SCHEMBL1372426 | 0.72 | ALDH1A1 (0.41) | MAPK1LMNAALDH1A1ALOX15 | |
| SCHEMBL4380616 | 0.67 | — | — | |
| SCHEMBL28396604 | 0.65 | — | — | |
| SCHEMBL11368195 | 0.65 | EGLN3 (0.57) | MAPK1EGLN3LMNAALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27814717 | 0.64 | LMNA (0.60) | MAPK1EGLN3LMNAALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL4739951 | 0.61 | LMNA (0.82) | MAPK1LMNAALKBH5SUCNR1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12233132-B2 | Polyoxazoline-lipid conjugates and lipid nanoparticles and pharmaceutical compositions including same | SERINA THERAPEUTICS, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| US-20240108750-A1 | POLYOXAZOLINE-LIPID CONJUGATES AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITIONS INCLUDING SAME | SERINA THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | US | disclosed |
| EP-4291242-A1 | POLYOXAZOLINE-LIPID CONJUGATES AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITIONS INCLUDING SAME | Serina Therapeutics, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-117098558-A | Polyoxazoline-lipid conjugates, lipid nanoparticles comprising same, and pharmaceutical compositions | 塞瑞纳治疗公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20220249695-A1 | POLYOXAZOLINE-LIPID CONJUGATES AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITIONS INCLUDING SAME | SERINA THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12233132-B2 | Polyoxazoline-lipid conjugates and lipid nanoparticles and pharmaceutical compositions including same | RNMT, SPOP, PLIN5 | MAPK1 4506/4885EGLN3 390/4885ESR1 4755/4885 |
| US-20220249695-A1 | POLYOXAZOLINE-LIPID CONJUGATES AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITIONS INCLUDING SAME | RNMT, SPOP, PLIN5 | MAPK1 4506/4885EGLN3 390/4885ESR1 4755/4885 |
| US-20240108750-A1 | POLYOXAZOLINE-LIPID CONJUGATES AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITIONS INCLUDING SAME | RNMT, SPOP, PLIN5 | MAPK1 4506/4885EGLN3 390/4885ESR1 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.