Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670899 | 0.81 | DGAT1 (0.38) | DGAT1ALDH1A1GAATSHRHSD17B10 | |
| SCHEMBL27518667 | 0.78 | — | — | |
| SCHEMBL3322447 | 0.75 | — | — | |
| SCHEMBL16863947 | 0.74 | GAA (0.47) | DGAT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9511958 | 0.74 | CES2 (0.37) | DGAT1HSD17B10MEN1KMT2AL3MBTL1 | |
| SCHEMBL27794147 | 0.73 | ALDH1A1 (0.35) | DGAT1ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL1012634 | 0.72 | DGAT1 (0.42) | DGAT1ALDH1A1GAATSHRHSD17B10 | |
| SCHEMBL18116696 | 0.71 | DGAT1 (0.33) | DGAT1ALDH1A1GAATSHRMEN1 | |
| SCHEMBL9509805 | 0.71 | CES2 (0.47) | HSD17B10MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL9508290 | 0.71 | CES2 (0.47) | HSD17B10MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750778-A | FLUOROALKANOIC ACIDS AND DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0468681-B1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| EP-0468681-A1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |