Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883731 | 0.89 | ACMSD (0.55) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL28442421 | 0.86 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HDAC4HDAC2 | |
| SCHEMBL84188 | 0.82 | SLC6A2 (0.66) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL29916354 | 0.82 | BCAT2 (0.63) | FABP3FABP4FABP5ALDH1A1GAA | |
| SCHEMBL30610922 | 0.82 | SLC6A2 (0.66) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL570758 | 0.82 | BCAT2 (0.63) | FABP3FABP4FABP5ALDH1A1GAA | |
| SCHEMBL29618929 | 0.82 | SLC6A2 (0.66) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL31621280 | 0.81 | SLC6A2 (0.64) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 | |
| Bromide SCHEMBL7032662 | 0.81 | SLC6A2 (0.64) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL31621279 | 0.81 | SLC6A2 (0.64) | ACMSDSLC6A2SLC6A4SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138011-A1 | TEREPHTHALIC ACID DERIVATIVE HAVING RING-FUSED STRUCTURE | 第一三共株式会社 | 2020-07-02 | — | — | WO | disclosed |
| EP-0876330-A1 | ARYL OR HETEROARYL AMIDES OF TETRAHYDRONAPHTHALENE, CHROMAN, THIOCHROMAN AND 1,2,3,4-TETRAHYDROQUINOLINE CARBOXYLIC ACIDS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997019052-A1 | ARYL OR HETEROARYL AMIDES OF TETRAHYDRONAPHTHALENE, CHROMAN, THIOCHROMAN AND 1,2,3,4-TETRAHYDROQUINOLINE CARBOXYLIC ACIDS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1997-05-29 | — | — | WO | disclosed |