Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672242 | 0.76 | APOBEC3A (0.37) | KCNJ5KCNJ3ADORA2AADORA1ALOX5AP | |
| SCHEMBL8671760 | 0.71 | TDP1 (0.45) | KCNJ5KCNJ3ADORA2AADORA1KDM4E | |
| SCHEMBL8669728 | 0.70 | ALOX5AP (0.36) | KCNJ5KCNJ3ADORA2AADORA1ALOX5AP | |
| SCHEMBL3877857 | 0.70 | MEN1 (0.35) | NPC1MAPTTDP1 | |
| SCHEMBL9730937 | 0.70 | ALDH1A1 (0.35) | KDM4ENPC1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL8674069 | 0.69 | MEN1 (0.34) | ADORA2AADORA1ALOX5APKDM4EALDH1A1 | |
| SCHEMBL9730966 | 0.67 | KDM4E (0.38) | KCNJ5KCNJ3KDM4EALDH1A1MAPT | |
| SCHEMBL11995530 | 0.65 | SMN1; SMN2 (0.46) | SLC6A2SLC6A4SLC6A3F9KDM4E | |
| SCHEMBL24970936 | 0.65 | ADRB1 (0.43) | KDM4ENPC1ALDH1A1POLBMAPT | |
| SCHEMBL31142946 | 0.65 | ADRB1 (0.43) | KDM4ENPC1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104884-A | Rheumatic diseases, fungicides | ALKALOIDA VEGYESZETI GYAR (HU) | 1992-04-14 | — | — | US | disclosed |
| EP-0221947-A1 | TRIAZOLYL QUINOLINE DERIVATIVES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-05-20 | — | — | EP | disclosed |
| WO-1986006721-A1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1986-11-20 | — | — | WO | disclosed |