Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673938 | 0.89 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1ALOX15HTR2C | |
| SCHEMBL8671940 | 0.87 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1ALOX15 | |
| SCHEMBL8883217 | 0.77 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL8600249 | 0.77 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8669828 | 0.75 | KMT2A (0.49) | MTNR1AMTNR1BALDH1A1ALOX15 | |
| SCHEMBL7741711 | 0.74 | MTNR1A (0.59) | MTNR1AMTNR1B | |
| SCHEMBL10449718 | 0.74 | LDHA (0.64) | ALDH1A1ALOX15 | |
| SCHEMBL9352780 | 0.74 | LDHA (0.64) | ALDH1A1ALOX15 | |
| SCHEMBL9352784 | 0.74 | LDHA (0.64) | ALDH1A1ALOX15 | |
| SCHEMBL7010632 | 0.73 | MTNR1A (0.55) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |