Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563917 | 0.85 | AR (0.53) | ARFASNPARP1GSK3BCDK5 | |
| SCHEMBL3794091 | 0.81 | AR (0.55) | ARFASNPARP1GSK3BCDK5 | |
| SCHEMBL4703362 | 0.78 | CHEK1 (0.67) | PARP1GSK3BCDK5CDK5R1CCNB2 | |
| SCHEMBL8667677 | 0.78 | CDK2 (0.50) | PARP1GSK3BCDK5CDK5R1CCNB2 | |
| SCHEMBL11455694 | 0.78 | FASN (0.57) | ARFASNPARP1GSK3BCDK5 | |
| SCHEMBL31357829 | 0.77 | GAA (0.60) | ARFASNGSK3BCDK5CDK5R1 | |
| SCHEMBL21563919 | 0.75 | NOS3 (0.46) | ARPARP1CDK2 | |
| SCHEMBL28446100 | 0.74 | CHUK (0.56) | ARFASNPARP1GSK3BCDK5 | |
| SCHEMBL8668538 | 0.74 | ABCG2 (0.62) | GSK3BCDK2MEN1KMT2AL3MBTL1 | |
| SCHEMBL97395 | 0.74 | BRD4 (0.60) | ARFASNPARP1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649406-B1 | CARBAZOLE DERIVATIVES AND THEIR USE IN COSMETICS, ESPECIALLY FOR MAKE-UP | OREAL (FR) | 1998-12-23 | — | — | EP | claimed |
| US-5543436-A | USED AS PIGMENTS IN COSMETICS, PARTICULARLY INTENDED FOR TREATMENT AND/OR COLORATION OF KERATINOUS SUBSTANCES | L'OREAL (FR) | 1996-08-06 | — | — | US | claimed |
| US-5543436-A | USED AS PIGMENTS IN COSMETICS, PARTICULARLY INTENDED FOR TREATMENT AND/OR COLORATION OF KERATINOUS SUBSTANCES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |