Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235191 | 0.94 | KCNMA1 (0.41) | GRIA1GRIA2GRIA3GRIA4KCNMA1 | |
| SCHEMBL8668562 | 0.85 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4KCNMA1 | |
| SCHEMBL9093233 | 0.81 | KCNMA1 (0.42) | GRIA1GRIA2GRIA3GRIA4KCNMA1 | |
| SCHEMBL8671549 | 0.80 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8670492 | 0.76 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8673721 | 0.76 | ALDH1A1 (0.46) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8671733 | 0.76 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9235018 | 0.76 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4KCNMA1 | |
| SCHEMBL9234206 | 0.76 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8673230 | 0.75 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | claimed |
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |