Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675576 | 0.81 | MAOB (0.48) | SLC6A2TAAR1CYP2D6LMNAMAOB | |
| SCHEMBL9288541 | 0.73 | SLC6A2 (0.48) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL15111556 | 0.72 | MAOB (0.48) | SLC6A2TAAR1MAOBTRPA1ALDH1A1 | |
| SCHEMBL74275 | 0.72 | MAOB (0.67) | TAAR1MAOBTRPA1ALDH1A1TP53 | |
| SCHEMBL1047440 | 0.72 | TAAR1 (0.56) | SLC6A2TAAR1CYP2D6LMNAMAOB | |
| SCHEMBL5164402 | 0.70 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL185486 | 0.69 | MAOB (0.55) | MAOBTRPA1CYP3A4ALDH1A1TP53 | |
| SCHEMBL8121696 | 0.69 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNAMAOB | |
| SCHEMBL7666090 | 0.69 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL1900874 | 0.69 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |