Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 0.70 |
| ▸ | HEXB | P07686 | 6/20 | 0.70 |
| ▸ | OGA | O60502 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalimidopropylamine SCHEMBL12502105 | 0.83 | HEXA (1.00) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL626424 | 0.82 | HEXA (1.00) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL8984898 | 0.81 | KDM4E (0.58) | HEXAHEXBOGAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28259369 | 0.81 | HEXA (0.96) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL5094701 | 0.78 | HEXA (1.00) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL6601488 | 0.77 | HEXA (0.97) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL9092483 | 0.77 | HEXA (0.82) | HEXAHEXBOGALCKSIRT1 | |
| Hydrochloric Acid SCHEMBL5748029 | 0.77 | HEXA (0.82) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL10396736 | 0.76 | HEXA (0.69) | HEXAHEXBOGALCKSIRT1 | |
| SCHEMBL9626265 | 0.76 | HEXA (0.83) | HEXAHEXBOGASIRT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789418-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |