Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 1.00 |
| ▸ | HEXB | P07686 | 6/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | RAD52 | P43351 | 1/20 | 0.63 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.61 |
| ▸ | OGA | O60502 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601488 | 0.98 | HEXA (0.97) | HEXAHEXBLCKKMT2AMEN1 | |
| Naphthalimidopropylamine SCHEMBL12502105 | 0.95 | HEXA (1.00) | HEXAHEXBLCKKMT2AMEN1 | |
| SCHEMBL9626265 | 0.91 | HEXA (0.83) | HEXAHEXBKMT2AMEN1POLB | |
| SCHEMBL9625535 | 0.90 | HEXA (0.81) | HEXAHEXBKMT2AMEN1POLB | |
| SCHEMBL9625779 | 0.90 | HEXA (0.81) | HEXAHEXBKMT2AMEN1POLB | |
| SCHEMBL9625395 | 0.90 | HEXA (0.81) | HEXAHEXBKMT2AMEN1POLB | |
| SCHEMBL9625518 | 0.90 | HEXA (0.81) | HEXAHEXBKMT2AMEN1POLB | |
| SCHEMBL626424 | 0.88 | HEXA (1.00) | HEXAHEXBLCKKMT2AMEN1 | |
| SCHEMBL25868576 | 0.86 | SIRT1 (0.79) | HEXAHEXBLCKKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28259369 | 0.86 | HEXA (0.96) | HEXAHEXBLCKKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109554004-B | Pigment dispersants and their use | 江苏丽王科技股份有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-109554004-A | Pigment dispersing agent and application thereof | 江苏丽王科技股份有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-109554004-B | Pigment dispersants and their use | 江苏丽王科技股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-109554004-A | Pigment dispersing agent and application thereof | 江苏丽王科技股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-103948595-B | Acid imide position or 4-position substituted 1,8-naphthalimide derivative is as the purposes of PARP inhibitor | 华侨大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-103948595-A | Use of imide site or 4-substituted 1, 8-naphthyl imide derivatives as PARP (poly adeno-sine diphosphate ribose polymerase) inhibitors | UNIV HUAQIAO | 2014-07-30 | — | — | CN | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| EP-1042291-B1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2005-07-13 | — | — | EP | disclosed |
| EP-1042315-B1 | CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2004-04-14 | — | — | EP | disclosed |
| EP-1042315-A1 | CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031087-A1 | CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |