Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 5/20 | 0.97 |
| ▸ | HEXB | P07686 | 5/20 | 0.97 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094701 | 0.98 | HEXA (1.00) | HEXAHEXBLCKSIRT1CYP3A4 | |
| Naphthalimidopropylamine SCHEMBL12502105 | 0.93 | HEXA (1.00) | HEXAHEXBLCKSIRT1CYP3A4 | |
| SCHEMBL9625535 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625779 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625395 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625518 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9626265 | 0.90 | HEXA (0.83) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL626424 | 0.86 | HEXA (1.00) | HEXAHEXBLCKSIRT1CYP3A4 | |
| SCHEMBL25868576 | 0.85 | SIRT1 (0.79) | HEXAHEXBLCKSIRT1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28259369 | 0.85 | HEXA (0.96) | HEXAHEXBLCKSIRT1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042315-B1 | CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2004-04-14 | — | — | EP | disclosed |
| EP-1042315-A1 | CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031087-A1 | CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |