Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.45 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671875 | 0.91 | KDM4E (0.44) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL2318952 | 0.85 | KDM4E (0.50) | KDM4ENPC1RAB9AGAABCHE | |
| SCHEMBL15567911 | 0.82 | KDM4E (0.51) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL8670655 | 0.81 | SMN1; SMN2 (0.51) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL29549500 | 0.80 | MAOA (0.58) | MAOAMAOBNPC1RAB9AMEN1 | |
| SCHEMBL429910 | 0.80 | MAOA (0.58) | MAOAMAOBNPC1RAB9AMEN1 | |
| SCHEMBL723458 | 0.80 | BCHE (0.53) | KDM4ENPC1RAB9AGAABCHE | |
| SCHEMBL8776563 | 0.80 | NPC1 (0.47) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL22215905 | 0.80 | KDM4E (0.51) | KDM4ENPC1RAB9AGAABCHE | |
| SCHEMBL8674540 | 0.79 | MAOB (0.71) | MAOAMAOBKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |