Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | UBE2I | P63279 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871034 | 0.80 | KMT2A (0.38) | MAPTHTR2AMEN1NSD2ALDH1A1 | |
| SCHEMBL8666857 | 0.80 | KMT2A (0.38) | MAPTHTR2AMEN1NSD2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8666991 | 0.79 | KMT2A (0.37) | MAPTHTR2AMEN1NSD2ALDH1A1 | |
| SCHEMBL8665662 | 0.74 | HDAC2 (0.40) | GAAMEN1POLBKMT2A | |
| SCHEMBL8668534 | 0.74 | SMN1; SMN2 (0.46) | MAPTGAAMEN1ALDH1A1POLB | |
| SCHEMBL8689402 | 0.73 | MEN1 (0.35) | MAPTMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL8685324 | 0.73 | L3MBTL1 (0.38) | MAPTMEN1POLBRECQLKMT2A | |
| SCHEMBL8666219 | 0.73 | KMT2A (0.34) | GAAMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8689708 | 0.72 | MEN1 (0.35) | MAPTMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL4019694 | 0.72 | SMYD3 (0.58) | SMYD3MAPTGAAHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |