Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | UBE2I | P63279 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666857 | 1.00 | KMT2A (0.38) | KMT2AMEN1CYP3A4CYP2C9MMP3 | |
| Hydrochloric Acid SCHEMBL8666991 | 0.99 | KMT2A (0.37) | KMT2AMEN1CYP3A4CYP2C9MMP3 | |
| SCHEMBL8685324 | 0.92 | L3MBTL1 (0.38) | KMT2AMEN1CYP3A4CYP2C9MMP3 | |
| SCHEMBL8689402 | 0.92 | MEN1 (0.35) | KMT2AMEN1CYP3A4CYP2C9MMP3 | |
| Hydrochloric Acid SCHEMBL8689708 | 0.91 | MEN1 (0.35) | KMT2AMEN1CYP3A4CYP2C9MMP3 | |
| SCHEMBL8684161 | 0.89 | MAPT (0.40) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL8684306 | 0.89 | MEN1 (0.37) | KMT2AMEN1CYP3A4CYP2C9NSD2 | |
| SCHEMBL8684526 | 0.87 | CYP2C19 (0.43) | KMT2AMEN1POLBMAPTL3MBTL1 | |
| SCHEMBL8684165 | 0.86 | CYP3A4 (0.43) | CYP3A4CYP2C9LMNATSHRRAB9A | |
| SCHEMBL8683694 | 0.86 | KMT2A (0.41) | KMT2AMEN1CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |