Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668250 | 0.84 | POLB (0.46) | SMN1; SMN2HTTPOLBATMKMT2A | |
| SCHEMBL8665662 | 0.82 | HDAC2 (0.40) | SMN1; SMN2LMNAPOLBGAAKMT2A | |
| SCHEMBL8871034 | 0.78 | KMT2A (0.38) | LMNATSHRPOLBKMT2AMEN1 | |
| SCHEMBL8666857 | 0.78 | KMT2A (0.38) | LMNATSHRPOLBKMT2AMEN1 | |
| SCHEMBL8666837 | 0.78 | HTT (0.43) | SMN1; SMN2HTTPOLBGAAKMT2A | |
| Hydrochloric Acid SCHEMBL8666991 | 0.78 | KMT2A (0.37) | LMNATSHRPOLBKMT2AMEN1 | |
| SCHEMBL8666307 | 0.76 | GRM5 (0.38) | SMN1; SMN2LMNATSHRGAAKMT2A | |
| SCHEMBL8670259 | 0.74 | SMYD3 (0.36) | POLBGAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL8685324 | 0.72 | L3MBTL1 (0.38) | POLBATMKMT2AMEN1USP2 | |
| SCHEMBL8689402 | 0.72 | MEN1 (0.35) | LMNAHTTPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |