Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.34 |
| ▸ | MME | P08473 | 5/20 | 0.34 |
| ▸ | CPA1 | P15085 | 4/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 3/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871974 | 0.78 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5871880 | 0.78 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6225204 | 0.75 | LAP3 (0.48) | ACEMMEPSEN1PSEN2APH1B | |
| SCHEMBL5872214 | 0.75 | LAP3 (0.48) | ACEMMEPSEN1PSEN2APH1B | |
| SCHEMBL7454879 | 0.74 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Hydrochloric Acid SCHEMBL8665816 | 0.73 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8664644 | 0.72 | CTSD (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8568989 | 0.71 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7402232 | 0.71 | CTSD (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7394330 | 0.71 | CTSD (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750648-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1998-05-12 | — | — | US | disclosed |