Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084509 | 0.96 | HTR2C (0.50) | HTR2CP2RY14ALDH1A1LMNAMAPT | |
| SCHEMBL8084510 | 0.96 | HTR2C (0.50) | HTR2CP2RY14ALDH1A1LMNAMAPT | |
| SCHEMBL8667366 | 0.87 | HTR2C (0.47) | HTR2CDGAT1SOAT1P2RY14ESR2 | |
| SCHEMBL8095319 | 0.84 | ALDH1A1 (0.54) | HTR2CDGAT1SOAT1P2RY14ALDH1A1 | |
| SCHEMBL8095323 | 0.84 | ALDH1A1 (0.54) | HTR2CDGAT1SOAT1P2RY14ALDH1A1 | |
| SCHEMBL9274076 | 0.82 | DRD2 (0.42) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL9274071 | 0.82 | DRD2 (0.42) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11282617 | 0.82 | HTR2C (0.51) | HTR2CDGAT1SOAT1P2RY14ALDH1A1 | |
| SCHEMBL8072502 | 0.82 | HTR2C (0.51) | HTR2CDGAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL8072503 | 0.82 | HTR2C (0.51) | HTR2CDGAT1SOAT1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811029-A | DIELECTRIC ANISOTROPY, CHEMICAL RESISTANCE, STORAGE STABILITY; ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-09-22 | — | — | US | disclosed |
| US-5389295-A | Electrooptic display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0438575-B1 | BENZOL DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0438575-A1 | BENZOL DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1991-07-31 | — | — | EP | disclosed |
| WO-1991002710-A2 | BENZOL DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |