Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084509 | 1.00 | HTR2C (0.50) | HTR2CALDH1A1LMNAMAPTESR2 | |
| SCHEMBL8670460 | 0.96 | HTR2C (0.46) | HTR2CALDH1A1LMNAMAPTESR2 | |
| SCHEMBL8072503 | 0.86 | HTR2C (0.51) | HTR2CALDH1A1LMNAMAPTESR2 | |
| SCHEMBL8072502 | 0.86 | HTR2C (0.51) | HTR2CALDH1A1LMNAMAPTESR2 | |
| SCHEMBL8997288 | 0.82 | ALDH1A1 (0.57) | HTR2CALDH1A1LMNAMAPTESR2 | |
| SCHEMBL8667366 | 0.82 | HTR2C (0.47) | HTR2CESR2IDO1P2RY14 | |
| SCHEMBL12926325 | 0.82 | L3MBTL1 (0.42) | ALDH1A1LMNAMAPTESR2CYP2C9 | |
| SCHEMBL9267879 | 0.81 | DRD2 (0.45) | ALDH1A1LMNAMAPTESR2CYP2C9 | |
| SCHEMBL9267883 | 0.81 | DRD2 (0.45) | ALDH1A1LMNAMAPTESR2CYP2C9 | |
| SCHEMBL9347904 | 0.81 | ALDH1A1 (0.56) | HTR2CALDH1A1LMNAMAPTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000136159-A | BENZENE DERIVATIVE AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH | 2000-05-16 | — | — | JP | disclosed |
| US-5811029-A | DIELECTRIC ANISOTROPY, CHEMICAL RESISTANCE, STORAGE STABILITY; ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-09-22 | — | — | US | disclosed |
| US-5389295-A | Electrooptic display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0438575-B1 | BENZOL DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0438575-A1 | BENZOL DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1991-07-31 | — | — | EP | disclosed |
| WO-1991002710-A2 | BENZOL DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |