Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667849 | 0.95 | HTR2A (0.36) | HTR2AHRH1MEN1ALDH1A1HTT | |
| SCHEMBL8666555 | 0.88 | MAPT (0.35) | HTR2AHRH1ALDH1A1HTTKMT2A | |
| SCHEMBL8664336 | 0.81 | DNM1 (0.38) | SIGMAR1ALDH1A1 | |
| SCHEMBL8658131 | 0.81 | HTR2A (0.36) | HTR2AHRH1ALDH1A1 | |
| SCHEMBL7770558 | 0.80 | DNM1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL3452063 | 0.80 | DNM1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL8670477 | 0.80 | DNM1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL7771807 | 0.80 | DNM1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL2448855 | 0.80 | MAPT (0.37) | SIGMAR1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL4722361 | 0.75 | TP53 (0.33) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |