Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662266 | 0.91 | MCHR1 (0.40) | MCHR1CCKBRMETAP2NOTUMDRD2 | |
| SCHEMBL8662936 | 0.86 | MCHR1 (0.40) | MCHR1CCKBRMETAP2NOTUMDRD2 | |
| SCHEMBL9267232 | 0.84 | LIPE (0.46) | MCHR1CCKBRMETAP2NOTUMDRD2 | |
| SCHEMBL8552381 | 0.82 | MCHR1 (0.47) | MCHR1NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL8662424 | 0.82 | MCHR1 (0.39) | MCHR1CCKBRMETAP2NOTUMDRD2 | |
| SCHEMBL6507723 | 0.80 | DRD2 (0.42) | MCHR1NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL8885582 | 0.79 | DRD2 (0.42) | MCHR1METAP2NOTUMDRD2DRD3 | |
| SCHEMBL8788951 | 0.74 | NOTUM (0.42) | MCHR1METAP2NOTUMDRD2DRD3 | |
| SCHEMBL8093681 | 0.74 | NOTUM (0.45) | MCHR1METAP2NOTUMDRD2DRD3 | |
| SCHEMBL8556361 | 0.74 | DRD2 (0.44) | MCHR1METAP2NOTUMDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1203599-A | Substitued pyrrolidinone, thiazolidinone or oxazolidinone as herbicides | ZENECA LTD (GB) | 1998-12-30 | — | — | CN | disclosed |
| EP-0863894-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| WO-1997020838-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |