Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 4/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867058 | 1.00 | KDM4E (0.39) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL866707 | 0.98 | KDM4E (0.39) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL866709 | 0.98 | KDM4E (0.39) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL867243 | 0.95 | KDM4E (0.39) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL867241 | 0.95 | KDM4E (0.39) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL866468 | 0.94 | KDM4E (0.41) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL866466 | 0.94 | KDM4E (0.41) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL865592 | 0.91 | KDM4E (0.41) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL865594 | 0.91 | KDM4E (0.41) | KDM4ELMNAMAPTMEN1POLB | |
| SCHEMBL867334 | 0.90 | LMNA (0.37) | KDM4ELMNAMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557922-B2 | Photocrosslinkable materials | ROLIC AG (CH) | 2013-10-15 | — | — | US | disclosed |
| US-20130004679-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2013-01-03 | — | — | US | disclosed |
| US-8329823-B2 | Photocrosslinkable materials | ROLIC AG (CH) | 2012-12-11 | — | — | US | disclosed |
| US-8173749-B2 | Photocrosslinkable materials | ROLIC AG (CH) | 2012-05-08 | — | — | US | disclosed |
| US-20120076952-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-20080293888-A1 | Photocrosslinkable Materials | ROLIC AG (CH) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293888-A1 | Photocrosslinkable Materials | DDC, PARG, ALAD | KDM4E 1831/4885LMNA 2057/4885MAPT 295/4885 |
| US-20120076952-A1 | PHOTOCROSSLINKABLE MATERIALS | DDC, PARG, ALAD | KDM4E 1831/4885LMNA 2057/4885MAPT 295/4885 |
| US-20130004679-A1 | PHOTOCROSSLINKABLE MATERIALS | DDC, PARG, ALAD | KDM4E 1831/4885LMNA 2057/4885MAPT 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.