Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172671 | 0.85 | HDAC1 (0.64) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10316555 | 0.82 | RELA (0.44) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10317064 | 0.82 | RELA (0.44) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7493543 | 0.80 | RELA (0.46) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9559166 | 0.80 | RELA (0.46) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9170505 | 0.79 | TBXAS1 (0.42) | HDAC1HDAC8ALDH1A1MEN1KMT2A | |
| SCHEMBL27651447 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1RELAPTGS1 | |
| SCHEMBL536967 | 0.78 | RELA (0.47) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7705710 | 0.78 | RELA (0.47) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29263660 | 0.77 | HDAC1 (0.59) | HDAC1HDAC8ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |