Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950234 | 0.75 | — | — | |
| SCHEMBL1357307 | 0.72 | CA1 (0.46) | LMNACA1CA2CA9IDO1 | |
| SCHEMBL2590168 | 0.71 | CA1 (0.44) | ATMTAAR1CA1CA2CA9 | |
| SCHEMBL8376179 | 0.71 | CA1 (0.47) | TAAR1MAOAMAOBCA1CA2 | |
| SCHEMBL3157759 | 0.71 | CA1 (0.40) | ATMTAAR1OPRM1DRD3CA1 | |
| SCHEMBL22728397 | 0.71 | OPRM1 (0.44) | ATMTAAR1MAOAMAOBLMNA | |
| SCHEMBL8374954 | 0.71 | CA1 (0.40) | ATMTAAR1OPRM1DRD3CA1 | |
| SCHEMBL8378726 | 0.68 | CA1 (0.41) | ATMTAAR1CA1CA2CA9 | |
| SCHEMBL1357308 | 0.68 | TDP1 (0.43) | LMNACA1CA2CA9IDO1 | |
| SCHEMBL8669946 | 0.68 | RAB9A (0.41) | LMNACA1CA2CA9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763465-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |