Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728407 | 0.91 | OPRM1 (0.42) | OPRM1DRD3DRD2DRD4EBP | |
| SCHEMBL22728409 | 0.89 | SIGMAR1 (0.43) | OPRM1DRD3DRD2DRD4EBP | |
| SCHEMBL2436941 | 0.78 | DRD2 (0.45) | OPRM1DRD3DRD2DRD4EBP | |
| SCHEMBL10766520 | 0.75 | TAAR1 (0.45) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL11824172 | 0.75 | DRD2 (0.46) | OPRM1DRD3DRD2DRD4EBP | |
| SCHEMBL16079189 | 0.74 | DRD2 (0.42) | OPRM1DRD3DRD2DRD4EBP | |
| SCHEMBL14477302 | 0.74 | DRD2 (0.46) | OPRM1DRD3DRD2DRD4EBP | |
| SCHEMBL11066485 | 0.72 | TP53 (0.44) | OPRM1DRD3LMNATP53ALDH1A1 | |
| SCHEMBL11224549 | 0.72 | TDP1 (0.50) | LMNATP53ALDH1A1HPGDALOX15 | |
| SCHEMBL21058275 | 0.71 | TAAR1 (0.45) | TP53ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |