Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298310 | 0.86 | NPC1 (0.51) | SMN1; SMN2KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL8560497 | 0.79 | RAB9A (0.43) | SMN1; SMN2KDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL9514491 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2KDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL27416808 | 0.75 | CHRM5 (0.44) | SMN1; SMN2KDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL8667992 | 0.75 | RELA (0.43) | SMN1; SMN2KDM4EALDH1A1L3MBTL1RELA | |
| SCHEMBL8670245 | 0.74 | MEN1 (0.54) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL8204171 | 0.73 | RELA (0.53) | SMN1; SMN2KDM4EALDH1A1L3MBTL1RELA | |
| SCHEMBL8668861 | 0.73 | RAB9A (0.51) | SMN1; SMN2KDM4EALDH1A1L3MBTL1RELA | |
| SCHEMBL7763925 | 0.73 | CYP1A2 (0.52) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL27318059 | 0.71 | MEN1 (0.53) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |