Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667895 | 0.91 | L3MBTL1 (0.42) | TSHRHTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL8666487 | 0.85 | GAA (0.35) | HPGDL3MBTL1CYP2C9POLBNPC1 | |
| SCHEMBL8669022 | 0.78 | KMT2A (0.46) | HTTSMN1; SMN2HPGDCYP2C9POLB | |
| SCHEMBL8672377 | 0.78 | ALDH1A1 (0.38) | TSHRHTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL14191187 | 0.76 | TSHR (0.75) | TSHRHTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL5175506 | 0.73 | KDM4E (0.39) | SMN1; SMN2HPGDL3MBTL1POLBRAB9A | |
| SCHEMBL5965196 | 0.73 | TSHR (0.60) | TSHRHTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL8672251 | 0.73 | ALDH1A1 (0.38) | TSHRHTTPOLBCYP1A2CYP2C19 | |
| SCHEMBL4049576 | 0.72 | L3MBTL1 (0.42) | TSHRHTTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL6882657 | 0.72 | L3MBTL1 (0.42) | TSHRHTTSMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |