Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666487 | 0.83 | GAA (0.35) | KMT2AGAAHSD17B10HPGDPOLB | |
| SCHEMBL8667895 | 0.81 | L3MBTL1 (0.42) | KMT2AGAALMNAHPGDPOLB | |
| SCHEMBL7990577 | 0.81 | KMT2A (0.47) | KMT2AGAAHSD17B10LMNAHPGD | |
| SCHEMBL8672251 | 0.80 | ALDH1A1 (0.38) | KMT2ALMNAMLYCDPOLBNPSR1 | |
| SCHEMBL8672377 | 0.79 | ALDH1A1 (0.38) | KMT2AGAAHSD17B10HPGDPOLB | |
| SCHEMBL8670976 | 0.78 | TSHR (0.50) | HPGDPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14947473 | 0.75 | ADRA1D (0.59) | KMT2AGAAHSD17B10LMNAHPGD | |
| SCHEMBL5175506 | 0.74 | KDM4E (0.39) | GAAHSD17B10HPGDPOLBNPSR1 | |
| SCHEMBL4983838 | 0.72 | KMT2A (0.51) | KMT2AGAAHSD17B10LMNAHPGD | |
| SCHEMBL159472 | 0.68 | KMT2A (0.63) | KMT2AGAAHSD17B10LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |