Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27816609 | 0.82 | TLR4 (0.47) | TLR4TLR2KDM5AKDM4CNR1H4 | |
| SCHEMBL510470 | 0.81 | TLR4 (0.63) | TLR4TLR2MAOAMAOBNR1H4 | |
| SCHEMBL8670655 | 0.78 | SMN1; SMN2 (0.51) | MAOAMAOB | |
| SCHEMBL4569068 | 0.77 | TLR4 (0.61) | TLR4TLR2MAOAMAOB | |
| SCHEMBL8674540 | 0.77 | MAOB (0.71) | TLR4TLR2MAOAMAOB | |
| SCHEMBL27996038 | 0.77 | TLR4 (0.48) | TLR4TLR2MAOAMAOB | |
| SCHEMBL3967903 | 0.77 | TLR4 (0.54) | TLR4TLR2MAOAMAOB | |
| SCHEMBL16902898 | 0.76 | KDM5A (0.48) | TLR4TLR2MAOAMAOBKDM5A | |
| SCHEMBL11942141 | 0.76 | ALDH1A1 (0.51) | TLR4TLR2KDM5AKDM4C | |
| SCHEMBL1408716 | 0.76 | TLR4 (0.47) | TLR4TLR2MAOBKDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |