Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | RARG | P13631 | 4/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668910 | 0.84 | RARA (0.45) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL8197285 | 0.80 | AKR1B1 (0.33) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL8293244 | 0.76 | RARA (0.49) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL18211725 | 0.76 | MAP3K14 (0.50) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9817812 | 0.76 | RARB (0.48) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9817629 | 0.76 | CYP26A1 (0.45) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL23266155 | 0.75 | RARA (0.46) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL6037049 | 0.75 | RARB (0.67) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9817831 | 0.75 | RARB (0.40) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9053722 | 0.75 | RARA (0.48) | RARARARBRARGRXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824685-A | VISION DEFECTS AND GENE EXPRESSION | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-10-20 | — | — | US | claimed |
| US-5824685-A | VISION DEFECTS AND GENE EXPRESSION | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-10-20 | — | — | US | disclosed |