Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491199 | 0.93 | ALDH1A1 (0.56) | GAAMAPTALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL29394763 | 0.84 | MAPT (0.51) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL12877586 | 0.79 | HTT (0.45) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL10990414 | 0.77 | GAA (0.67) | GAAMEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL16032835 | 0.75 | ALDH1A1 (0.48) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL16032837 | 0.75 | ALDH1A1 (0.48) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL491245 | 0.74 | ALDH1A1 (0.54) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL7436149 | 0.74 | GAA (0.62) | GAAMEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL28349386 | 0.74 | GAA (0.62) | GAAMEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL28612690 | 0.74 | GAA (0.62) | GAAMEN1KMT2ATSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278464-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278464-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-02 | — | — | US | disclosed |
| CN-101394742-B | Anthranilamide derivatives and their use for the control of insects and acari | SYNGENTA PARTICIPATIONS AG | 2012-05-23 | — | — | CN | disclosed |
| US-20120077991-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, LLC | 2012-03-29 | — | — | US | disclosed |
| US-20120077991-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, LLC | 2012-03-29 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| EP-2213167-A1 | Anthranilamide derivatives and their use for the control of insects and acari | Syngenta Participations AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| EP-2213167-A1 | Anthranilamide derivatives and their use for the control of insects and acari | Syngenta Participations AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| CN-101394742-A | Anthranilamide derivatives and their use for the control of insects and acari | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-25 | — | — | CN | disclosed |
| EP-1976385-A2 | ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI | Syngeta Participations AG (CH) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007080131-A2 | ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI | SYNGENTA PARTICIPATIONS AG (CH) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007080131-A2 | ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI | SYNGENTA PARTICIPATIONS AG (CH) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077991-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | GAA 3060/4885MAPT 160/4885ALDH1A1 155/4885 |
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | GAA 2476/4885MAPT 100/4885ALDH1A1 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.