Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 5/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731612 | 0.83 | IMPDH2 (0.43) | IMPDH2AOC1AOC3LOXL2GABRA1 | |
| SCHEMBL11614582 | 0.80 | AOC1 (0.52) | IMPDH2AOC1AOC3LOXL2CA12 | |
| SCHEMBL30660479 | 0.78 | IMPDH2 (0.51) | IMPDH2AOC1AOC3LOXL2GABRA1 | |
| SCHEMBL15821545 | 0.78 | IMPDH2 (0.40) | IMPDH2AOC1AOC3LOXL2GABRA1 | |
| SCHEMBL1631793 | 0.76 | — | — | |
| SCHEMBL2642717 | 0.74 | — | — | |
| SCHEMBL370783 | 0.73 | IMPDH2 (0.40) | IMPDH2AOC1AOC3LOXL2GABRA1 | |
| SCHEMBL8038467 | 0.73 | AOC1 (0.59) | IMPDH2AOC1AOC3LOXL2GABRA1 | |
| SCHEMBL23674728 | 0.73 | KDM4C (0.50) | ALDH1A1 | |
| SCHEMBL13714209 | 0.73 | IMPDH2 (0.37) | IMPDH2GABRA1GABRB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |