Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064593 | 0.94 | RARB (0.47) | POLBL3MBTL1GAATP53TSHR | |
| SCHEMBL14174513 | 0.93 | POLB (0.42) | POLBL3MBTL1GAATP53TSHR | |
| SCHEMBL13871217 | 0.86 | POLB (0.41) | POLBL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4412768 | 0.86 | MAPK1 (0.41) | POLBL3MBTL1TP53TSHRPLA2G4B | |
| SCHEMBL4112542 | 0.86 | ALDH1A1 (0.37) | POLBTP53TSHRPLA2G4BLMNA | |
| SCHEMBL2798093 | 0.84 | KMT2A (0.54) | POLBL3MBTL1GAATP53TSHR | |
| SCHEMBL13871215 | 0.83 | POLB (0.39) | POLBL3MBTL1TP53TSHRNPC1 | |
| SCHEMBL4419384 | 0.83 | POLB (0.36) | POLBL3MBTL1TP53TSHRNPC1 | |
| SCHEMBL10713224 | 0.82 | TP53 (0.58) | L3MBTL1GAATP53TSHRPLA2G4B | |
| SCHEMBL3976660 | 0.81 | ADRB2 (0.44) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | claimed |
| EP-0281941-A2 | Coreactive photoinitiators | CIBA-GEIGY AG (CH) | 1988-09-14 | — | — | EP | claimed |
| US-5837746-A | Coreactive photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| US-5744512-A | Coreactive photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |
| US-5532112-A | PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0416395-B1 | Platy, surface-modified substrate | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | disclosed |
| EP-0416395-A2 | Platy, surface-modified substrate | MERCK PATENT GmbH (DE) | 1991-03-13 | — | — | EP | disclosed |
| US-4833035-A | Oriented polymer materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-23 | — | — | US | disclosed |
| EP-0281941-A2 | Coreactive photoinitiators | CIBA-GEIGY AG (CH) | 1988-09-14 | — | — | EP | disclosed |
| EP-0254949-A2 | Orientated polymeric material | MERCK PATENT GmbH (DE) | 1988-02-03 | — | — | EP | disclosed |