SCHEMBL4419384

SCHEMBL4419384

CCO[Si](CCCC(CC(=O)O)C(=O)OCCOc1ccc(C(=O)C(C)(C)O)cc1)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
SLC2A1 P11166 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
PLA2G4B P0C869 2/20 0.34
HTT P42858 1/20 0.34
MAPK1 P28482 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
RARB P10826 2/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13871203 0.89 CA1 (0.36) MMP9MMP13
SCHEMBL13871215 0.88 POLB (0.39) POLBSLC2A1MEN1KMT2ATDP1
SCHEMBL8673385 0.83 POLB (0.44) POLBPLA2G4BTP53TSHRL3MBTL1
SCHEMBL4412768 0.82 MAPK1 (0.41) POLBSLC2A1PLA2G4BHTTMAPK1
SCHEMBL9064593 0.80 RARB (0.47) POLBPLA2G4BTP53TSHRRARB
SCHEMBL13871217 0.80 POLB (0.41) POLBMEN1KMT2AL3MBTL1NPC1
SCHEMBL14174513 0.79 POLB (0.42) POLBKMT2APLA2G4BTP53TSHR
SCHEMBL13871202 0.78 MET (0.36)
SCHEMBL4112542 0.76 ALDH1A1 (0.37) POLBPLA2G4BTP53TSHR
SCHEMBL28479377 0.74 CPB2 (0.39) MEN1KMT2ATDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367743-B2 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces BASF SE (DE) 2013-02-05 US disclosed
US-8367743-B2 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces BASF SE (DE) 2013-02-05 US disclosed
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces IGM GROUP B.V. (NL) 2009-04-23 US disclosed
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces IGM GROUP B.V. (NL) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces CDH1, PCNA, VCAM1 POLB 403/4885SLC2A1 4072/4885MEN1 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.