Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556791 | 0.80 | CYP1A2 (0.43) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL9664290 | 0.76 | MAPK1 (0.74) | SMN1; SMN2NPC1RAB9AMAPK1GBA1 | |
| SCHEMBL4504096 | 0.75 | LCK (0.67) | SMN1; SMN2NPC1RAB9AMAPK1GBA1 | |
| SCHEMBL30711612 | 0.75 | LCK (0.67) | SMN1; SMN2NPC1RAB9AMAPK1GBA1 | |
| SCHEMBL6697640 | 0.74 | ALDH1A1 (0.49) | LCKMAPTLMNACYP1A2KMT2A | |
| SCHEMBL14097068 | 0.74 | LCK (0.66) | SMN1; SMN2NPC1RAB9AMAPK1GBA1 | |
| SCHEMBL50044 | 0.73 | LCK (0.60) | SMN1; SMN2NPC1RAB9AMAPK1GBA1 | |
| SCHEMBL30797275 | 0.73 | RAB9A (0.58) | SMN1; SMN2NPC1RAB9AMAPK1MAPT | |
| SCHEMBL3560505 | 0.72 | CYP1A2 (0.41) | SMN1; SMN2RAB9AMAPK1MAPTCYP1A2 | |
| SCHEMBL12182431 | 0.72 | MAPK1 (0.65) | SMN1; SMN2NPC1RAB9AMAPK1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750547-A | Certain carbanate anti-cancer agents | UNIVERSITE LAVAL (CA) | 1998-05-12 | — | — | US | disclosed |