Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.65 |
| ▸ | RXRB | P28702 | 11/20 | 0.65 |
| ▸ | RARB | P10826 | 9/20 | 0.65 |
| ▸ | RXRG | P48443 | 8/20 | 0.65 |
| ▸ | RARG | P13631 | 8/20 | 0.65 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.63 |
| ▸ | RARA | P10276 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319350 | 0.82 | CYP26A1 (0.71) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL29827631 | 0.80 | RARB (0.81) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL846110 | 0.80 | RARB (0.81) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL9318594 | 0.80 | RXRA (0.70) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL8460878 | 0.80 | RXRA (0.70) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL7723487 | 0.79 | RXRA (1.00) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL8674121 | 0.79 | RXRA (0.69) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL9522831 | 0.79 | CYP3A4 (0.60) | RXRARXRBRARBRXRGRARG | |
| Hydrochloric Acid SCHEMBL9120757 | 0.78 | RARB (0.78) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL15554765 | 0.78 | RXRA (0.67) | RXRARXRBRARBRXRGRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386451-B1 | OXYGEN-BEARING DIPHENYL HETEROALKANES, PROCESS FOR THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1993-04-28 | — | — | EP | disclosed |
| US-5128479-A | Skin disorders, cosmetics | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| EP-0386451-A1 | Oxygen-bearing diphenyl heteroalkanes, process for their preparation and use | BASF Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | disclosed |