Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17035392 | 0.94 | TSHR (0.44) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL23908692 | 0.91 | LMNA (0.50) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL13042886 | 0.90 | LMNA (0.41) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL1054764 | 0.89 | TSHR (0.52) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL19700255 | 0.89 | TSHR (0.43) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL12405770 | 0.89 | TSHR (0.43) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL23860276 | 0.86 | TSHR (0.48) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| Azelaic Acid SCHEMBL8198302 | 0.85 | TSHR (0.52) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL4967244 | 0.85 | TSHR (0.38) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL512941 | 0.85 | TSHR (0.48) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10330382-A | — | — | None | — | — | JP | disclosed |
| JP-H10330382-A | PRECURSOR COMPOUND AND AROMATIC MATERIAL | GIVAUDAN ROURE INTERNATL SA | 1998-12-15 | — | — | JP | disclosed |