Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NOTCH1 | P46531 | 5/20 | 0.37 |
| ▸ | NOTCH3 | Q9UM47 | 4/20 | 0.37 |
| ▸ | NOTCH2 | Q04721 | 1/20 | 0.37 |
| ▸ | NOTCH4 | Q99466 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672565 | 0.91 | CCKBR (0.52) | CCKBRKCNH2FNTAFNTBNOTCH1 | |
| SCHEMBL8669411 | 0.77 | CCKBR (0.43) | CCKBRKCNH2FNTAFNTBNOTCH1 | |
| SCHEMBL8674499 | 0.77 | CCKBR (0.46) | CCKBRKCNH2FNTAFNTBHDAC3 | |
| SCHEMBL8801061 | 0.76 | FNTA (0.46) | CCKBRKCNH2FNTAFNTBHDAC3 | |
| SCHEMBL8940402 | 0.75 | FNTA (0.46) | CCKBRKCNH2FNTAFNTB | |
| SCHEMBL8672484 | 0.75 | KCNH2 (0.43) | CCKBRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL8668005 | 0.75 | CCKBR (0.48) | CCKBRKCNH2FNTAFNTBSCN9A | |
| SCHEMBL8801333 | 0.74 | FNTA (0.52) | CCKBRFNTAFNTBCCKAR | |
| SCHEMBL8800232 | 0.73 | OXTR (0.49) | CCKBRKCNH2CCKAR | |
| SCHEMBL8674221 | 0.73 | CCKBR (0.51) | CCKBRKCNH2SCN9ACCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |