Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | CCKAR | P32238 | 2/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677103 | 0.91 | CCKBR (0.42) | CCKBRKCNH2CCKAROXTR | |
| SCHEMBL8674219 | 0.83 | CCKBR (0.47) | CCKBRKCNH2SCN9ACCKAR | |
| SCHEMBL8668005 | 0.81 | CCKBR (0.48) | CCKBRKCNH2SCN9ASENP1OXTR | |
| SCHEMBL8674499 | 0.79 | CCKBR (0.46) | CCKBRKCNH2CCKAR | |
| SCHEMBL8667984 | 0.75 | CCKBR (0.42) | CCKBRKCNH2CCKAROXTR | |
| SCHEMBL8801061 | 0.74 | FNTA (0.46) | CCKBRKCNH2CCKAROXTR | |
| SCHEMBL8800232 | 0.74 | OXTR (0.49) | CCKBRKCNH2CCKAROXTR | |
| SCHEMBL8800784 | 0.74 | CCKBR (0.46) | CCKBRKCNH2CCKARSENP1OXTR | |
| SCHEMBL8672484 | 0.74 | KCNH2 (0.43) | CCKBRKCNH2CCKAROXTR | |
| SCHEMBL8801839 | 0.73 | CCKBR (0.50) | CCKBRCCKAROXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |