Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673214 | 0.83 | MAPT (0.47) | CTSBMAPTALDH1A1L3MBTL1CTSH | |
| SCHEMBL8677060 | 0.81 | PTGER4 (0.39) | CTSBMAPTALDH1A1PTGER4APP | |
| SCHEMBL8672851 | 0.77 | NQO2 (0.43) | MAPTALDH1A1PTGER4LCKKDM4E | |
| SCHEMBL8677062 | 0.77 | GRM2 (0.43) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL4995737 | 0.75 | MAPK1 (0.50) | MAPTL3MBTL1PTGER4LCKKDM4E | |
| SCHEMBL8548121 | 0.75 | CTSB (0.60) | CTSBMAPTALDH1A1L3MBTL1CTSH | |
| SCHEMBL25320720 | 0.74 | SIRT6 (0.43) | MAPTALDH1A1VCAM1LMNAKDM4E | |
| SCHEMBL31413102 | 0.74 | SIRT6 (0.43) | MAPTALDH1A1VCAM1LMNAKDM4E | |
| SCHEMBL11388218 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1L3MBTL1VCAM1LMNA | |
| SCHEMBL4934807 | 0.73 | MAPT (0.41) | MAPTALDH1A1VCAM1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827653-A | COMPLEMENTARY PROBE HYBRIDIZATION AND FORMATION OF A CHELATED LANTHANIDE COMPLEX, WHICH UPON IRRADIATION BY LIGHT, RESULTS IN A CHARACTERISTIC DELAYED LUMINESCENCE EMISSION | ZENECA LIMITED (GB) | 1998-10-27 | — | — | US | disclosed |
| EP-0720659-A1 | NUCLEIC ACID DETECTION WITH ENERGY TRANSFER | ZENECA LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008642-A1 | NUCLEIC ACID DETECTION WITH ENERGY TRANSFER | ZENECA LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |