Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674378 | 0.85 | BID (0.46) | MYCBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27892555 | 0.84 | SMN1; SMN2 (0.45) | LTB4R2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL28342495 | 0.83 | CYP3A4 (0.48) | KEAP1NFE2L2LTB4R2LMNAMAPT | |
| SCHEMBL27547212 | 0.82 | LMNA (0.44) | KEAP1NFE2L2LTB4R2BIDMCL1 | |
| SCHEMBL25181813 | 0.81 | FOLH1 (0.53) | LTB4R2BIDMCL1BCL2L1BAK1 | |
| Benzene SCHEMBL28299279 | 0.81 | KMT2A (0.51) | LTB4R2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL38662910 | 0.80 | BID (0.52) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL3706715 | 0.80 | BID (0.52) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL1002853 | 0.79 | MAPT (0.53) | LTB4R2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL1513987 | 0.79 | HNF4A (0.53) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862555-A1 | SUBSTITUTED ARYL OR HETEROARYLAMIDES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019062-A1 | SUBSTITUTED ARYL OR HETEROARYLAMIDES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1997-05-29 | — | — | WO | disclosed |