Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674735 | 0.86 | PSMB5 (0.44) | LTB4RLTB4R2ADORA3PDCD1CD274 | |
| SCHEMBL4506021 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1GAAHPGDLTB4R | |
| SCHEMBL4279832 | 0.83 | LIPG (0.44) | MAPTPSMB5 | |
| SCHEMBL22497560 | 0.81 | LTB4R (0.41) | KDM4EALDH1A1GAAHPGDLTB4R | |
| SCHEMBL28166881 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAHPGDADORA3 | |
| SCHEMBL27948004 | 0.77 | PSMB5 (0.49) | HPGDPSMB5 | |
| SCHEMBL27747958 | 0.76 | TAAR1 (0.44) | BACE1DPP4PSMB5 | |
| SCHEMBL6139588 | 0.76 | PDCD1 (0.47) | KDM4EALDH1A1GAAHPGDLTB4R | |
| SCHEMBL27681638 | 0.75 | BACE1 (0.50) | KDM4EALDH1A1GAAHPGDLTB4R | |
| SCHEMBL28581876 | 0.75 | NPC1 (0.44) | KDM4EALDH1A1GAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557532-B | Bigeminy benzene derivative and its application | 西安力邦制药有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-104557532-A | Biphenyl derivative and application thereof | XI AN LIBANG PHARMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | disclosed |
| US-5847040-A | Lower alkyl biphenyls as plasticizers for polyurethane | KOCH INDUSTRIES, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5696184-A | EPOXY POLYMER CONTAINING DIISOPROPYLBIPHENYL AND/OR TRIISOPROPYLBIPHENYL; INCREASED FLEXIBILITY AND TOUGHNESS | KOCH INDUSTRIES, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-5489646-A | CAN USE HIGH LOAD LEVELS | KOCH INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |