SCHEMBL5069000

SCHEMBL5069000

O=C(O)c1cnc2c(c1)cc(C(=O)O)c1cccnc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.52
L3MBTL1 Q9Y468 4/20 0.50
KDM4A O75164 2/20 0.50
EGLN1 Q9GZT9 2/20 0.50
KDM6B O15054 1/20 0.50
KDM6A O15550 1/20 0.50
TET3 O43151 1/20 0.50
KDM4B O94953 1/20 0.50
KDM5C P41229 1/20 0.50
KDM4D Q6B0I6 1/20 0.50
TET2 Q6N021 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
TET1 Q8NFU7 1/20 0.50
FTO Q9C0B1 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
KDM2A Q9Y2K7 1/20 0.50
KDM3A Q9Y4C1 1/20 0.50
PSMD14 O00487 2/20 0.47
MGAM O43451 1/20 0.45
ALDH1A1 P00352 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679992 0.85 KDM4E (0.60) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL21358078 0.80 PSMD14 (0.60) KDM4EPSMD14MGAMALDH1A1RAB9A
SCHEMBL10611260 0.77 KDM4E (0.59) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL27611353 0.75 LMNA (0.54) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL8674711 0.75 KDM4E (0.54) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL17178165 0.74 KDM4E (0.52) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL1087851 0.74 PSMD14 (0.64) KDM4EKDM4AEGLN1KDM6BTET3
SCHEMBL31058237 0.74 PSMD14 (0.64) KDM4EKDM4AEGLN1KDM6BTET3
SCHEMBL17174167 0.74 KDM4E (0.49) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL10464809 0.73 PSMD14 (0.50) KDM4EPSMD14MGAMALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1901363-A1 LUMINESCENT DEVICE AND ELECTROLUMINESCENCE UTILIZING THE SAME Gifu University (JP) 2008-03-19 EP claimed