Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7932854 | 0.99 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL9727207 | 0.89 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL4215401 | 0.89 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL8677765 | 0.87 | SIGMAR1 (0.54) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL9239027 | 0.87 | DRD2 (0.54) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL11393302 | 0.87 | SIGMAR1 (0.54) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9242362 | 0.86 | DRD2 (0.52) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9243515 | 0.86 | DRD2 (0.52) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7933015 | 0.86 | SIGMAR1 (0.53) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7935858 | 0.86 | SIGMAR1 (0.53) | CHRM2CHRM1CHRM3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2785879-B2 | — | — | 1998-08-13 | — | — | JP | claimed |
| EP-0552246-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1993-07-28 | — | — | EP | claimed |
| WO-1992006967-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-04-30 | — | — | WO | claimed |
| EP-0476016-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| WO-1990015047-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | claimed |