Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839974 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1TDP1ATM | |
| SCHEMBL11219221 | 0.84 | SRC (0.47) | L3MBTL1KMT2ATDP1ATMCYP2D6 | |
| SCHEMBL11319434 | 0.81 | SRC (0.53) | L3MBTL1KMT2ATDP1ATMCYP2D6 | |
| SCHEMBL8675334 | 0.79 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1TDP1ATM | |
| SCHEMBL11310800 | 0.78 | L3MBTL1 (0.47) | L3MBTL1KMT2ATDP1ATMCYP2D6 | |
| SCHEMBL10961231 | 0.77 | L3MBTL1 (0.43) | L3MBTL1KMT2AMEN1TDP1ATM | |
| SCHEMBL7106510 | 0.77 | KMT2A (0.47) | L3MBTL1KMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL29819688 | 0.75 | CHRM1 (0.49) | KMT2ATDP1CYP2D6SRCLMNA | |
| SCHEMBL9051580 | 0.75 | KMT2A (0.45) | L3MBTL1KMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL11320690 | 0.74 | MMP8 (0.56) | L3MBTL1KMT2AMEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770775-B2 | REACTING ACID HALIDES WITH A CINCHONA ALKALOID CATALYST AND A BASE TO FORM INTERMEDIATE KETENES, WHICH ARE THEN REACTED WITH ELECTROPHILIC HALOGENATING REAGENTS TO PRODUCE ALPHA-HALO-ESTERS WITH HIGH ENANTIOMERIC EXCESS | WACK HARALD (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20030050501-A1 | Method of synthesizing optically enriched alpha-halo-esters, and product and composition therefrom | WACK HARALD (DE) | 2003-03-13 | — | — | US | disclosed |