Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372470 | 0.82 | NPC1 (0.52) | MAPTL3MBTL1KMT2ASMN1; SMN2ADRB2 | |
| SCHEMBL8673136 | 0.82 | PTGS2 (0.50) | MAPTGAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL19506910 | 0.80 | MAPT (0.42) | MAPTGAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL16561460 | 0.80 | MAPT (0.41) | MAPTGAAL3MBTL1ADRB2ADRB1 | |
| SCHEMBL3281422 | 0.79 | SMN1; SMN2 (0.62) | MAPTKMT2ASMN1; SMN2PLA2G4BALDH1A1 | |
| SCHEMBL16561606 | 0.78 | ELANE (0.45) | MAPTL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL19315946 | 0.77 | L3MBTL1 (0.40) | MAPTGAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL8673991 | 0.77 | CYP19A1 (0.47) | MAPTGAAL3MBTL1KMT2AAOC3 | |
| SCHEMBL8674750 | 0.77 | ALDH1A1 (0.43) | MAPTGAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL3977620 | 0.77 | L3MBTL1 (0.42) | MAPTGAAL3MBTL1MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744512-A | Coreactive photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-04-28 | — | — | US | claimed |
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | claimed |
| US-5837746-A | Coreactive photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| US-5532112-A | PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |