Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675421 | 1.00 | GCK (0.54) | GCKPTGER1USP2LMNACCR5 | |
| SCHEMBL8323098 | 0.90 | LMNA (0.54) | GCKPTGER1USP2LMNACCR5 | |
| SCHEMBL8323106 | 0.90 | LMNA (0.54) | GCKPTGER1USP2LMNACCR5 | |
| SCHEMBL8676532 | 0.86 | PTGER1 (0.59) | GCKPTGER1LMNAMAPTPTGER4 | |
| SCHEMBL8676537 | 0.86 | PTGER1 (0.59) | GCKPTGER1LMNAMAPTPTGER4 | |
| SCHEMBL8675593 | 0.84 | GCK (0.76) | GCKPTGER1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL8325873 | 0.83 | GCK (0.53) | GCKPTGER1LMNAPTGER4PTGER3 | |
| SCHEMBL8325877 | 0.83 | GCK (0.53) | GCKPTGER1LMNAPTGER4PTGER3 | |
| SCHEMBL2167875 | 0.78 | PTGER4 (0.67) | PTGER1USP2LMNACCR5PTPN1 | |
| SCHEMBL2167870 | 0.78 | PTGER4 (0.67) | PTGER1USP2LMNACCR5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |