Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.76 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326477 | 0.91 | GCK (0.69) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL2642055 | 0.87 | GCK (1.00) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL2642100 | 0.87 | GCK (1.00) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL8675421 | 0.84 | GCK (0.54) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL8675423 | 0.84 | GCK (0.54) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL8676537 | 0.84 | PTGER1 (0.59) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL8676532 | 0.84 | PTGER1 (0.59) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL8325873 | 0.83 | GCK (0.53) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL8325877 | 0.83 | GCK (0.53) | GCKPTGER1PTGER4PTGER2PTGER3 | |
| SCHEMBL14519324 | 0.80 | GCK (0.79) | GCKPTGER1PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |