Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CTSV | O60911 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459732 | 0.86 | PTGER1 (0.66) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8675451 | 0.83 | PTGER1 (0.56) | PTGER1PTGER4PTGER3PTGER2GAA | |
| SCHEMBL8676578 | 0.82 | MEN1 (0.52) | MEN1KMT2ACTSVCTSLPTGER1 | |
| SCHEMBL8676630 | 0.81 | MTNR1A (0.55) | KDM4ESMN1; SMN2PTGER1PTGER4PTGER3 | |
| SCHEMBL8675205 | 0.81 | PTGER1 (0.71) | PTGER1PTGER4PTGER3PTGER2SGMS2 | |
| SCHEMBL8677127 | 0.81 | RAB9A (0.56) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8675899 | 0.81 | PTGER1 (0.54) | KDM4EPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676388 | 0.80 | PTGER1 (0.55) | CTSVCTSLPTGER1PTGER4PTGER3 | |
| SCHEMBL8322219 | 0.80 | PTGER1 (0.52) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8322247 | 0.80 | CYP19A1 (0.56) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |