Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515061 | 0.79 | NPSR1 (0.40) | ALDH1A1KDM4EDRD3KCNH2DRD2 | |
| SCHEMBL18835681 | 0.75 | ERCC1 (0.59) | ERCC1ERCC4ALDH1A1KDM4EDRD3 | |
| SCHEMBL8672693 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4EKCNH2KMT2AL3MBTL1 | |
| SCHEMBL4517574 | 0.71 | P2RX7 (0.47) | ALDH1A1KDM4EDRD3HPGDDRD2 | |
| SCHEMBL15038459 | 0.71 | ERCC1 (0.54) | ERCC1ERCC4ALDH1A1KDM4EDRD3 | |
| SCHEMBL8671469 | 0.69 | KMT2A (0.53) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL10399987 | 0.68 | L3MBTL1 (0.67) | ERCC1ERCC4ALDH1A1KDM4EKCNH2 | |
| SCHEMBL1276590 | 0.68 | ALDH1A1 (1.00) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2HRH3 | |
| SCHEMBL11227514 | 0.68 | ALDH1A1 (1.00) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2HRH3 | |
| SCHEMBL4749240 | 0.68 | ERCC1 (0.55) | ERCC1ERCC4ALDH1A1DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726188-A | TREATING SENILE DEMENTIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |