SCHEMBL8947347

SCHEMBL8947347

O=S(=O)(O)c1c(/N=N/c2c(O)ccc3ccccc23)ccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 5/20 0.63
CTRC Q99895 2/20 0.63
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
TSHR P16473 1/20 0.62
PTPRA P18433 1/20 0.62
PTPRB P23467 1/20 0.62
CYP2C19 P33261 1/20 0.62
HIF1A Q16665 1/20 0.62
RAPGEF4 Q8WZA2 1/20 0.62
HSD17B10 Q99714 1/20 0.62
MAPT P10636 7/20 0.59
MAPK1 P28482 4/20 0.59
KMT2A Q03164 4/20 0.59
TDP1 Q9NUW8 4/20 0.59
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 4/20 0.57
KDM4E B2RXH2 2/20 0.57
NPC1 O15118 2/20 0.57
THRB P10828 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344640 1.00 MPL (0.63) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL29393603 1.00 MPL (0.63) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL29912833 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577832 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577835 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577808 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL9577763 0.99 MPL (0.61) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL14549104 0.90 CYP1A2 (0.79) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL10884144 0.89 CYP1A2 (0.60) MPLCTRCCYP1A2CYP2C9TSHR
SCHEMBL29617555 0.87 MPL (0.53) MPLCTRCCYP1A2CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-9362514-B2 Polarization organic photoelectric conversion device, method for producing polarization organic photoelectric conversion device, polarization optical device, imaging device, and electronic apparatus SONY CORPORATION (JP) 2016-06-07 US disclosed
US-9362514-B2 Polarization organic photoelectric conversion device, method for producing polarization organic photoelectric conversion device, polarization optical device, imaging device, and electronic apparatus SONY CORPORATION (JP) 2016-06-07 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed
US-8444715-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2013-05-21 US disclosed
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2012-11-01 US disclosed
US-20120248563-A1 POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR PRODUCING POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, POLARIZATION OPTICAL DEVICE, IMAGING DEVICE, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2012-10-04 US disclosed
US-20120248563-A1 POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR PRODUCING POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, POLARIZATION OPTICAL DEVICE, IMAGING DEVICE, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2012-10-04 US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 US disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MPL 4581/4885CTRC 830/4885CYP1A2 1159/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MPL 4581/4885CTRC 830/4885CYP1A2 1159/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MPL 4581/4885CTRC 830/4885CYP1A2 1159/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MPL 4581/4885CTRC 830/4885CYP1A2 1159/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MPL 4581/4885CTRC 830/4885CYP1A2 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.